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Vitamin D is the subject of great controversy in the medical field. Uncertainties surround its use, including how much to give, what forms to use, and so on. This book attempts to clear up the confusion by providing concise and comprehensive information on vitamin D. Chapters cover such topics as the earliest investigations of vitamin D, subsequent studies of extraskeletal consequences of vitamin D deficiency, and clinical application of correction of vitamin D.
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The 53rd National Congress of the Italian Society of Biochemistry and Molecular Biology (SIB), which will be held in Riccione from 23 to 26 September, is characterised by the elevated scientific level and interdisciplinary interest of the numerous sessions in which it is organised. The Scientific Programme comprises three joint Symposia of the SIB and the Chemistry of Biological Systems section of the Italian Chemistry Society (SCI) on Molecular Systems Biology, Chemistry of Nucleic Acids, Protein and Drug Structure, and Environmental Biotechnology. These Symposia address groundbreaking arguments, making the joint interest of the two societies particularly fascinating; the joint organisation of these events in fact signals the shared intention to proceed along the path of scientific exchange. The topics of the other sessions have been chosen by the Scientific Committee on the basis of their scientific relevance and topicality, with particular attention paid to the selection of the speakers. The SIB sessions will range from Signal Transduction and Biomolecular Targets, Protein Misfolding and its Relationship with Disease, Emerging Techniques in Biochemistry, Gene Silencing, Redox Signalling and Oxidative Stress, Lipids in Cell Communication and Signal Transduction, Mitochondrial Function and Dysfunction.
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Iron is an essential element for almost all organisms, a cofactor playing a crucial role in a number of vital functions, including oxygen transport, DNA synthesis, and respiration. However, its ability to exchange electrons renders excess iron potentially toxic, since it is capable of catalyzing the formation of highly poisonous free radicals. As a consequence, iron homeostasis is tightly controlled by sophisticated mechanisms that have been partially elucidated. Because of its biological importance, numerous disorders have been recently linked to the deregulation of iron homeostasis, which include not only the typical disorders of iron overload and deficiency but also cancer and neurodegenerative diseases. This leads iron metabolism to become an interesting therapeutic target for novel pharmacological treatments against these diseases. Several therapies are currently under development for hematological disorders, while other are being considered for different pathologies. The therapeutic targeting under study includes the hepcidin/ferroportin axis for the regulation of systemic iron homeostasis, complex cytosolic machineries for the regulation of the intracellular iron status and its association with oxidative damage, and reagents exploiting proteins of iron metabolism such as ferritin and transferrin receptor. A promising potential target is a recently described form of programmed cell death named ferroptosis, in which the role of iron is essential but not completely clarified. This Special Issue has the aim to summarize the state-of-the-art, and the latest findings published in the iron field, as well as to elucidate future directions.
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Inland lakes are indicators of climate change and environmental deterioration. As a unique ecosystem unit, an inland lake is one of the basic locations for human survival and development. In recent years, with the rapid development of regional society and economy, the ecological environment of inland lakes has been continuously disturbed by human activities under the influence of large-scale water and soil exploitation activities, which have affected the ecological environment of lakes. Therefore, lake ecological restoration and water quality monitoring under the coupled effect of climate change and human activities are the key to lake protection and management. In recent years, remote sensing has played an increasingly important role in the monitoring of the terrestrial water cycle. Remote sensing technology has been applied in many fields, such as water storage, water quality, water level, and hydrodynamics. Furthermore, the explosive growth of remote sensing data applications is driven by the coupling of multisource remote sensing data and the expansion of new modeling technology.
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Iron is an essential element for almost all organisms, a cofactor playing a crucial role in a number of vital functions, including oxygen transport, DNA synthesis, and respiration. However, its ability to exchange electrons renders excess iron potentially toxic, since it is capable of catalyzing the formation of highly poisonous free radicals. As a consequence, iron homeostasis is tightly controlled by sophisticated mechanisms that have been partially elucidated. Because of its biological importance, numerous disorders have been recently linked to the deregulation of iron homeostasis, which include not only the typical disorders of iron overload and deficiency but also cancer and neurodegenerative diseases. This leads iron metabolism to become an interesting therapeutic target for novel pharmacological treatments against these diseases. Several therapies are currently under development for hematological disorders, while other are being considered for different pathologies. The therapeutic targeting under study includes the hepcidin/ferroportin axis for the regulation of systemic iron homeostasis, complex cytosolic machineries for the regulation of the intracellular iron status and its association with oxidative damage, and reagents exploiting proteins of iron metabolism such as ferritin and transferrin receptor. A promising potential target is a recently described form of programmed cell death named ferroptosis, in which the role of iron is essential but not completely clarified. This Special Issue has the aim to summarize the state-of-the-art, and the latest findings published in the iron field, as well as to elucidate future directions.
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Tannins are one of the polyphenols group found in plants and are mainly studied because of their structural properties and bioactive behavior. Every year new findings concerning their properties and functions are made, and today concerns are mainly focused on how they can be used efficiently in the wood, food, textile, health, and pharmaceutical industries. Thus, the aim of this book is to present the most updated information on the structural properties of tannins, their food sources and variations, biological properties, and health, among other important issues. In addition, the most recent methods used for their isolation, quantifications, and industrial applications will also be covered.
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Chlorophyll, a green pigment present in almost all plants, algae, and cyanobacteria, is a significant biomolecule essential to photosynthesis, the process by which plants convert light into energy. This book provides a comprehensive and easy-to-understand source of information on the latest developments in chlorophyll research. It is a collection of contributions from leading specialists in the subject. Topics discussed include the medicinal uses of chlorophyll, the electronic structure of chlorophyll monomers and oligomers, and chlorophyll estimate from fluorescence vertical profiles in the ocean.
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Biology. --- Chemistry. --- Biochemistry. --- Biochemistry
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